Massachusetts State Police responded to a single vehicle car crash on Route 291 Eastbound at Exit 14 in Springfield.
A 54-year-old Springfield man was traveling in a Ford 150, when he lost control of the car and traveled off the right side of the exit ramp, striking a guardrail.
The driver was transported to Baystate Medical Center where he was pronounced dead.
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The cause of the crash is under investigation, and the identity of the victim is being withheld pending family notification.